Details for gene set INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB
Phenotype	phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB
Upregulated in class	transDMproB
GeneSet	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)
Enrichment Score (ES)	0.7257431
Normalized Enrichment Score (NES)	1.5154245
Nominal p-value	0.016544119
FDR q-value	0.39957675
FWER p-Value	0.993

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PSMB9	23021	277	2.071	0.0934	Yes
2	PSMB10	5299 18761	416	1.833	0.1818	Yes
3	SOCS3	20131	448	1.785	0.2735	Yes
4	PSMB1	23118	508	1.706	0.3596	Yes
5	PSMB6	9634	775	1.454	0.4213	Yes
6	PSMB8	5000	1132	1.179	0.4638	Yes
7	STAT1	3936 5524	1384	1.007	0.5030	Yes
8	PSMB5	9633	1607	0.915	0.5389	Yes
9	PSMA5	6464	1654	0.889	0.5829	Yes
10	STAT5A	20664	1660	0.884	0.6289	Yes
11	STAT4	14251 9907	1775	0.816	0.6654	Yes
12	PSMB3	11180	1944	0.724	0.6943	Yes
13	PSMA4	11179	2022	0.681	0.7257	Yes
14	PSMA2	9631	2917	0.334	0.6951	No
15	PSMB4	15252	3866	0.166	0.6528	No
16	PSMA3	9632 5298	4081	0.144	0.6489	No
17	PSMB7	2795 14598	4408	0.117	0.6374	No
18	STAT3	5525 9906	4604	0.106	0.6325	No
19	PSMA7	14318	4864	0.092	0.6233	No
20	STAT5B	20222	5176	0.079	0.6107	No
21	PSMD2	10137 5724	6511	0.043	0.5412	No
22	PSMA6	21270	6976	0.035	0.5181	No
23	PSMA1	1627 17669	12805	-0.037	0.2065	No
24	PSMB2	2324 16078	16450	-0.389	0.0309	No
25	STAT2	19840	16470	-0.397	0.0506	No
26	PSMC1	9635	17755	-1.238	0.0463	No

Fig 3: INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING): Random ES distribution
Gene set null distribution of ES for INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)